Explain Why Propanolol should be avoided in bronchial asthma

EXPLAIN WHY PROPANOLOL SHOULD BE AVOIDED IN BRONCHIAL ASTHMA
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Treatment of Bronchial Asthma is done by ß agonist ( selective ß2 agonist such as Salbutamol ). It acts by relaxing the human airway tract. ß2 agonist stimulates the ß2 adrenergic receptor present in Bronchus and dialates it.

Propanolol is a non-selective beta blocker opposite to the medication of broncial asthma. It is mainly used in patients to treat hypertension.

Propanolol can block both the ß1 and ß2 receptors.

Propanolol → ß1 + ß2 receptor antagonist → Blocks ß2 receptor in Bronchial smoot muscle → Broncospasm

So, Propanolol is contradicted in patients of Bronchial Asthma and COPD ( Chronic Obstructive Pulmonary Disorder )

That explain why Propranolol Should be avoided in bronchial asthma.

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http://www.medgag.com/katzung-trevors-pharmacology-examination-board-review/

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