The book is divided into 20 parts that cover broad topics such as the profession of medicine, cardinal manifestations and presentation of disease, oncology and hematology, immune-mediated, inflammatory, and rheumatological diseases, and disorders associated with environmental exposures. The parts are further divided into specific topic sections, such as pain, therapy for bacterial disease, neurologic critical care. Finally, these sections are subdivided into chapters covering conditions such as urticaria, angioedema, and allergic rhinitis, with lists of further reading suggestions. Throughout the book, there are a great number of full-color figures, algorithms, and intuitive tables to support the text. As readers become familiar with the book's format, it is very easy to use the pertinent patient management algorithm in the front cover page that refers them directly to the relevant page. There is also a listing of available videos; supplemental topics, such as microbial bioterrorism, technique of lumbar puncture; and atlases of rashes, oral manifestations of disease, and electrocardiography. An electronic version of the book is available for separate purchase through the AccessMedicinewebsite, which allows a 30-day trial subscription.